The 2010 Lexus GX 460 takes its model designation from an all-new 4.6-liter V8 engine. The new 32-valve DOHC engine features aluminum alloy cylinder heads and block with dual Variable Valve Timing with Intelligence (VVT-i), which controls valve timing and overlap on both the intake and exhaust camshafts to optimize power, fuel efficiency and emissions. (The previous 4.7 had VVT only on the intake camshafts.) Peak torque is also up for the new 4.6, now 329 lb.-ft. at 3,500 rpm vs. 323 lb.-ft. at 3,400 rpm for the 4.7-liter engine.

The new 4.6-liter V8 is teamed to a six-speed electronically controlled automatic transmission, compared to a five-speed automatic with the previous 4.7-liter, benefiting both performance and fuel economy. The new transmission fits in the same space as the previous five-speed and features a higher top gear ratio. The new powertrain helps make the 2010 Lexus GX 460 feel more responsive in everyday driving and quieter than the previous model. The 2010 Lexus GX 460 retains the same 6,500-lb. towing capacity as the GX 470 offered.

The Lexus GX 460 comes equipped with standard full-time four-wheel drive using an electronically controlled transfer case and a TORSEN® torque-sensing center differential. It also offers a low range for off-road driving. The TORSEN differential distributes power 40:60 under most driving conditions and changes the ratio as needed based on steering input and wheel slip.

The ability to change to a 30:70 ratio during steering maneuvers helps enhance vehicle tracking through curves. If the rear wheels spin, the center differential can change the ratio to 50:50 to help control the slippage. The TORSEN differential also helps make the Lexus GX 460 less prone to slippage caused by sudden changes in road-surface conditions, such as driving through a puddle or over an ice patch. The rear differential has also been strengthened for 2010.