The 2010 Lexus GX 460 is one of the few premium brand luxury utility vehicles that can deliver genuine trail driving capability. Combining that capability with Lexus luxury and on-road performance makes it even more exceptional. Lexus studied vehicle usage of current owners and found that many use their GX models for family hauling during the week and vacations and camping trips on weekends. They often tow a boat or watercraft and sometimes drive to areas with unpaved and rugged trails.

Like the previous GX 470, the 2010 GX 460 has robust body-on-frame construction and does not compromise on- or off-road performance; the high-strength chassis and dynamic suspension control technology support both.

The available Adaptive Variable Suspension (AVS) with three modes: Normal, Sport and Comfort, and independent front suspension delivers a smooth on-road ride without compromising rugged off-road capabilities. The 2010 Lexus GX 460 rides on larger standard 18-inch alloy wheels with 265/60 R18 tires, versus 17-inch wheels for the 2009 GX 470 model.

The power rack-and-pinion steering system helps make it easier to maneuver the Lexus GX 460 in tight spaces. Rear Adjustable Height Control (AHC) enhances the vehicle's flexibility in a wide range of driving situations.