The Lexus LS 460 flagship showcases the brand's L-finesse design philosophy, revealing a family resemblance that conveys elegance, refinement and a strong emotional appeal. Minimal body gaps, a low front grille and deep-drawn fenders all contribute to the car's distinctive, muscular profile. Lexus' attention to detail is seen in the integrated dual chrome exhaust tips and the one-piece chrome window surround.

Changes to the color palate for 2010 reflect the brand's focus on luxury design: Matador Red Mica replaces Nobel Spinel Mica; Satin Cashmere Metallic replaces Golden Almond Metallic; Peridot Mica replaces Verdigris Mica, and Deep Sea Mica replaces Black Sapphire Pearl.